Publications
Key publications
Novel assays monitoring direct glucocorticoid receptor protein activity exhibit high predictive power for ligand activity on endogenous gene targets. Van Moortel et al. Biomedicine & Pharmacotherapy, 2022. DOI: 10.1016/j.biopha.2022.113218.
Approaches towards tissue-selective pharmacology of the mineralocorticoid receptor. Clarisse et al. British Journal of Pharmacology, 2022. DOI: 10.1111/bph.15719.
Compound A attenuates proinflammatory cytokine-induced endoplasmic reticulum stress in beta cells and displays beneficial therapeutic effects in a mouse model of autoimmune diabetes. Andreone et al. Cellular and Molecular Life Sciences, 2022. DOI: 10.1007/s00018-022-04615-5.
Improved Glucocorticoid Receptor Ligands: Fantastic Beasts, but How to Find Them? Van Moortel et al. Frontiers in Endocrinology (Lausanne), 2020. DOI: 10.3389/fendo.2020.559673.
How the glucocorticoid receptor contributes to platinum-based therapy resistance in solid cancer. Clarisse et al. Nature Communications, 2021. DOI: 10.1038/s41467-021-24847-6.